Irish pole Conor Murray and Robbie Henshaw center were excluded for the last two fall tests for injury.
Murray's half-back Murray has got a neck injury and has not played since visiting Australia in June.
Leinster jumper Henshaw jumped in a warm-up balloon before winning Argentina on Saturday in Dublin.
Ireland's New Zealand play on Saturday and a week later in the United States.
Loss duo loss was significantly overtaken by Irish coach Joe Schmidt before the anticipated game Aviva Stadium against All Black.
New Zealand coach Steve Hansen said he expected Murray to play against All Black after his team had won over England.
Schmidt did not rule out the possibility of Murray, but despite the leverage "speeding up his recovery", Ireland confirmed on Monday that he will not play any role in the last two games.
Luke McGrath started halfway in Ireland to win over Italy in Chicago on November 3, while Kieran Marmion surrendered nine shirts against Argentina.
Henshaw, who missed much of this year's six-nation campaign for injury, did not travel for Chicago and retired a minute before Saturday's victory over Pumas 28-17.
Ulster's Will Addison was late in joining Puma, though Garry Ringrose favored Bundee's Aki midfielder when he was supposed to recover from the minor injuries that kept him last Saturday.