According to a new study, for patients taking medicines for the treatment of hypothyroidism, treatment with excessive medications can lead to increased risk of atrial fibrillation, a common stroke associated with stroke.
The findings were presented to researchers at the Intermountain Medical Institute at Salt Lake City at a conference organized by the American Heart Association in Chicago.
"We know that patients with hypothyroidism have a higher risk of atrial fibrillation, but have not considered an increased risk within what is considered a normal range of thyroid hormone." These findings indicate that we would like to reconsider what we call normal, "said chief researcher Jeffrey L Anderson.
The researchers investigated electronic medical records of 174,914 patients treated at Intermountain Healthcare facilities whose free thyroxine levels (fT4) were recorded and were not on replacement thyroid drugs. The researchers then took what was considered a normal range of fT4 levels, divided into four quartiles, and then reviewed the records of these patients for current or future diagnosis of atrial fibrillation.
They found 40 percent increase in existing atrial fibrillation in patients with the highest quartile of fT4 levels compared with patients at the lowest and 16 percent in new atrial fibrillation during 3-year follow-up.
These findings suggest that the optimal healthy range of fT4 should be re-examined and redefined, according to Dr. Anderson.
"Thyroid hormones are associated with weight loss and have more energy, which can lead to people being treated at the high end of the normal range." Did we harm humans by putting them at a higher risk of atrial fibrillation and therefore stroke? " is Dr. Anderson.
The study also showed that fT4 should be measured, together with a thyroid stimulating hormone (TSH), commonly tested in patients with irregular levels of thyroid hormone, but was not useful in the normal range of refinery risk.
"The next step for researchers to carry out randomized trials to determine whether lower or upper upper fT4 ranges in patients receiving substitution of thyroid hormone leads to lower risk of atrial fibrillation and stroke with other possible cardiac problems such as atherosclerosis" , said Dr. Anderson.
Posted: November 11, 2018 2:01 AM