New results of a 65-year follow-up study of nearly 7,000 Norwegians
patients with multiple sclerosis (MS) indicate that patients may have a
greater overall risk of developing cancer from the general population,
with a particularly high risk of cancer in the respiratory system, the urinary system
organ and central nervous system.
Presented today at the 5th European Academy of Neurology (EAN)
Congress in Oslo, Norway, Norwegian Studies also points to
increased risk of hematological cancer development in brothers and sisters who are not in the MS group
patients with MS compared to patients with MS and general
Cancer risk among MS patients compared to non-MS population:
- Respiratory system cancer: 66% increase in risk
- Central nervous system (CNS): 52% increase in risk
- Urinary tract: 51% increase in risk
- Total cancer: 14% increase in risk
This long-term analysis was based on patient data of 6,883 MSs
patients born between 1930 and 1997
Norwegian registry offices and cancer registers, and prevalence studies from Norway.
The analysis also included data from 8,918 brothers and sisters without MS, i
37,919 persons not members of the MS.
"This study is the first to compare the risk of cancer in MS
brothers and sisters of MS patients. Risk assessment between them
two groups are extremely interesting because they share the same genetics
and environmental conditions, "said Dr. Nina Grytten, lead researcher
studies, from Haukeland University Hospital, Bergen, which presented it
results at EAN congress.
"Previous Clinical Examination of Cancer Risk in MS Patients Different
the country showed inconsistent findings, so there are further researches
to help improve our understanding in this area, "said Dr
Grytten. "This research highlights the need for greater awareness of this
cancer risk among MS patients, which should lead to a shortening of cancer
diagnosis and more effective therapy to improve outcomes and
"Additional research can also identify possible links
between hematological cancer and MS and new ways we could
to manage those conditions, "she added.
Multiple sclerosis is a life-long illness that affects central illness
nervous system, especially the brain, spinal cord and optic nerve. It
can lead to a wide range of symptoms, including vision problems,
movement of hands or feet, feeling or balance. MS is one of the most common
causes of disability in younger adults and persons with MS
average 7 years shorter longevity.
Hematological cancer is a type of cancer of the blood that involves
myeloma, lymphoma and leukemia. There are many different types
hematologic cancers, which can affect blood, bone marrow and
lymph nodes in the body. According to Dr. Grytten, the results
the investigation may suggest that MS and haematological cancer may
share a common etiology, which may be important for future treatment
MS and the prevention of both diseases.
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