American researchers have created natural hair that grows through the skin, in what is being charged as a breakthrough in the treatment of baldness.
Scientists from Sanford Burnham Preby, California, achieved growth by pluripotent human-induced stem cells (iPSCs).
The results are presented at the annual International Stem Cell Research (ISSCR) meeting on Thursday.
The newly founded company, Stemson Therapeutics, licensed the technology.
Genetics, aging, delivery, cancer treatment, burns and medical disorders such as alopecia can cause hair loss.
The condition is often associated with emotional stress that can reduce the quality of life and lead to anxiety.
Alexey Terskikh is an Associate Professor at Sanford Burnham Prebys.
He says: "Our new protocol described today goes beyond the key technological challenges that have kept our discovery from actual use.
"Now we have a robust, highly controlled method of creating natural hair that grows through the skin using an unlimited source of human papillary cells that originate from iPSC.
"This is a critical development in the development of hair loss treatment at the cell and regenerative medicine area."
Terskikh studies the cell type called dermal papilla.
These cells are within the hair follicles and control hair growth – including hair thickness, length and growth cycle.
In 2015, hair grew under the skin of the mouse by creating dermal papilla obtained from human pluripotent stem cells.
Access has a 3D biodegradable skeleton made of the same material as soluble stitches.
The snout controls the direction of hair growth and helps the stem cells integrate into the skin, a natural strong barrier.
The current protocol relies on mouse epithelial cells in combination with human cellular papilloma.
Experiments were conducted in immunodeficient bare mice lacking hair.
Performing the epithelial part of the hair follicle from the human iPSC is underway at the Terskikh Laboratory.
Finasteride and Minoxidil are the current major treatments for male baldness.
Minoxidil can also be used to treat female baldness.
However, HSE says these treatments do not work for everyone, and they only work as long as they are used.