Teva Pharmaceuticals has voluntarily withdrawn the two medicines used to treat high blood pressure, as more drugs are facing with concern over possible cancer risk.

IN Teva statement published by the Food and Drug Administration, recall affects all combinations of medicines tablets amlodipine and valsartan and other combined medicines containing amlodipine, valsartan and hydrochlorothiazide.

The drugs may contain impurities called N-nitroso diethylamine (NDEA), which is classified as a possible human carcinogen, according to the FDA.

Patients taking medicines should contact their doctor or pharmacist for advice or alternative treatments. Stopping medication immediately without comparable alternatives could pose a higher risk to the health of patients, Teva said.

Users and patients with inquiries can contact Teva by phone at 888-838-2872 or by e-mail at

In August, the FDA announced an extended recall of valsartan because the products may contain impurities. Last month, two more withdrawals were announced: one for irbesartan and another withdrawal for losartan potassium hydrochlorothiazide tablets.

During a November interview with USA Today, FDA commissioner Scott Gottlieb said the blood pressure medicines reminded of increased focus on drug quality to ensure there were no impurities.

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