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Genetic variations can determine that somebody is early mouth



Genetics determine that some people get up early and have good waking up, which could generate greater benefit and reduce the risk of schizophrenia and depression, according to a study published today in Nature.

The research conducted by the University of Exeter (United R.) and the Massachusetts General Hospital (USA) throws light on the functioning of our biological clock from a genetic analysis of extensive databases.

Experts have come to associate early morning quality with mental health and some of the diseases that do not occur, need, diabetes or obesity, as it has been considered so far.

The study highlights the role of eye retina in helping the body to control time and also increases the number of genome areas that affect whether or not a mouth is 24 to 351.

"This paper reveals a large number of genes that can be studied in detail to understand how different people can have different biological clocks," said Mike Weedon of the Medical School at Exeter.

A large number of individuals involved in this research, he says, "gave us the clearest evidence that we are still getting" that "night birds have a greater risk of mental illness."

They have analyzed the genome of 250,000 individuals in the American database. and 450,000 from one in the United Kingdom, who were also asked whether they are "morning" or "nightmares".

After that, they tried to identify their genes in common and to influence their sleep patterns, while comparing this information with data from other 85,000 Biobank individuals who were equipped with a bracelet to counteract the subject's subjective subjectivity.

They noted that the identified genetic variants may change up to 25 minutes per hour in which the person naturally wakes, at passing, for example, from 08:00 to 08:25.

Identified genomic regions include those that affect our body clocks, known as "circadian rhythms," in which they also discovered the presence of genes expressed in the brain and retinal eye tissue.

The circle of the biological clock, they point out, is somewhat longer than the 24-hour diary and, therefore, the linkage of the eye tissue explains how the brain detects light to "reset" that clock every day and synchronizes it with the daily cycle.

Functioning of our biological clock, they add, under the influence of the genes and our lifestyle, such as eating, exposure to artificial light, and our jobs and activities.

We remember the Nobel Prize for Medicine that in 2017 set three American scientists to detect molecular mechanisms that control circadian rhythm, an "internal biological clock" that plants, animals and humans adapt to Earth's rotations.

"Our work shows that some of the reasons why some people get up early the other night because of differences in the way our brains respond to external light signals and the normal functioning of our watches." Samuel E. Jones from the University of Exeter.

These "small differences", he concludes, could have "significant effects" on the ability of our biological watches to "effectively control time," which could "change the risks associated with the disease and mental disorders."


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