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They found a new & # 39; blocker & # 39; bacterium



According to a study published in the journal Inmmunity, researchers from the National Center for Cardiovascular Research (CNIC) and the Department of Immunology at Complutense University in Madrid, a new "keeper of intestinal bacteria" was discovered.

A group of scientists from CNIC and immunology at Complutense University in Madrid observed a study of some types of bacteria living in the intestines, such as lactobacillus, strengthen the intestinal barrier favoring the relationship between existing mutual benefit and preventing inflammation.

There was also a connection between the diseases associated with the increased spread of the bacteria in the body, such as metabolic disturbances.

In turn, the director of Immunology CNIC, David Sancho, wanted to point out that the research "shows that there are molecules present or excreted by these intestinal bacteria that specifically bind to a receptor called" Mincle "(Clec4e) expressed in antigen-presenting cells of the immune system called dendritic cells and whose function is to strengthen the intestinal barrier.

What is the intestinal barrier responsible for?

The intestinal barrier function is to restrict the passage of & quot; coment & quot; microorganisms so that they remain only in the intestines. The activity carried out is a priority to avoid certain diseases or certain factors such as the type of food that may weaken the intestinal barrier and, as a consequence, generate systemic inflammation associated with autoimmune or metabolic diseases.

As a result, experts believe that a new strategy to reduce these pathologies may be the use of probiotics, "useful" microorganisms inhabiting intestines, or prebiotics, foods that favor the growth of these & quot; useful & quot; microorganisms may be present, although their mechanism of action for now is unknown.

Among the benefits we find in & quot; Mincle & quot ;, a greater immune response is noted, whose function is to keep these bacteria in the intestines. In addition, it prevents its spreading in the liver and other organs where it can cause inflammatory and metabolic disorders.


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