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Factors of stroke risk increase in postmenopausal women with breast cancer diagnosis

Stroke risk factors are rapidly growing in postmenopausal women in the first year after breast cancer diagnosis has been diagnosed, according to a preliminary study to be presented at Honolulu at the International Stroke Conference on the American Stroke Association in 2019, the World Premiere for Researchers and Clinicians dedicated to science and the treatment of cerebrovascular disease.

Cancer is a well-known risk factor for stroke, but it is not clear whether the risk of increased risk for long-term survival or whether stage cancer and hormone therapy affect stroke risk, particularly in postmenopausal breast cancer.

Researchers have studied changes in the Risk Assessment of Framingham's Risk (FSRS) after breast cancer diagnosis among women involved in the Virginia Cancer Registry. Of the 2,141 eligible women (mean age 64 years of diagnosis), there was complete information for calculating the Framingham risk of five factors in 616 women.

Researchers have found:

  • The average FSRS was 10.6 at diagnosis, which corresponds to a 6-percent probability of stroke in the next 10 years.
  • One year after the diagnosis, the FSRS increased to 16.07, trivializing the likelihood of stroke in the next 10 years (19 percent).
  • Minor increases occurred in 5 and 10 years, with a stroke probability of 23 to 10 years.
  • The most common individual risk factors were (43.3 percent), the other indicators (39.56 percent) and (23.11 percent).
  • The tumor stage was not associated with changes in stroke risk.
  • Hormone treatment is associated with a higher grade of stroke risk.
  • Non-Hispanic black women had higher FSRS than non-Hispanic white women.

"Prevention and control of high blood pressure and diabetes should be the target of intervention to reduce the risk of stroke among men after menopause," said Dr. Kyungeh An, Research Manager and Associate Professor of Surgery. at Virginia Commonwealth University in Richmond.

The study was limited by the small share of women in the registry who had all the available measurements for the FSRS calculation and the lack of a comparable group of women of similar age without breast cancer. The information from this study in Virginia can not be generalized to other populations.


Published in: News on Medical Research News on women's health

Tags: blood, blood pressure, breast cancer, cancer, cancer diagnosis, cerebrovascular disease, diabetes, disability, heart, high blood pressure, hormone therapy, care, pH, public health, research, stroke, tumor

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